84-1229-92 RAPSN (43kD Receptor-associated Protein of the Synapse, RAPsyn, 43kD Postsynaptic Protein, Acetylcholine Receptor-associated 43kD Protein, RING Finger Protein 205, RNF205) 100ug R1139-50E
84-1229-92 RAPSN (43kD Receptor-associated Protein of the Synapse, RAPsyn, 43kD Postsynaptic Protein, Acetylcholine Receptor-associated 43kD Protein, RING Finger Protein 205, RNF205) 100ug R1139-50E
Rapsyn (receptor-associated protein of the synapse) is a peripheral membrane protein that has a close association to acetylcholine receptors (AChRs).
Studies have shown that mice with a mutated rapsyn gene were unable to form AChR clusters, resulting in birth from respiratory failure death soon after.
Other mutations affecting the activity of rapsyn can lead to the formation of the neuromuscular disease myasthenia gravis.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Western Blot: 0.3-1ug/ml, observed in human skeletal muscle lysates on ~38kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human RAPSN. Species sequence homology: Mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to YQSNQTEKALQVWTK-C, from human RAPSN, at N-terminal (NP_005046.2, NP_116034.2).
