May act as an adapter protein to couple membrane receptors to intracellular signaling pathways.
May be involved in signaling of ITGB2/LFA-1 and other integrins.
Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.
Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation.
Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity.
Inhibits the kinase activity of DYRK1A and DYRK1B.
Inhibits FMR1 binding to RNA.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Immunohistochemistry (Paraffin): 3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human RANBP9. Species sequence homology: Canine, mouse and porcine.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Ca Hu Mo Po
Immunogen：Synthetic peptide corresponding to GSCAFATVEDYLH, from human RANB9, at C-terminal (NP_005484.2).
