Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
May promote the assembly of presynaptic RAD51 nucleoprotein filaments.
The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity.
The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:8000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes RAD51L1. Species sequence homology: Bovine, human and porcine.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Bo Hu Po
Immunogen:Synthetic peptide corresponding to GSKKLKRVGLSQE-C, from RAD51L1, at N-terminal (NP_002868.1, NP_598194.1, NP_598193.2).