Binds to the E-box consensus sequence 5'-CANNTG-3'.
Plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates.
May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase.
Required for the formation of pancreatic acinar and ductal cells.
Plays an important role in cerebellar development.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.5-1.5ug/ml, observed in human brain (cerebellum) lysates on ~48kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human PTF1A. Species Crossreactivity: Mouse. Species sequence homology: Canine, rat and zebrafish.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt Ze
Immunogen：Synthetic peptide corresponding to C-WTDEKQLKEQN, from PTF1A, at the internal region of the protein (NP_835455.1).
