Mutations in the PTEN-induced kinase (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease.
Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance.
Applications:Suitable for use in ELISA, Immunofluorescence and Flow Cytometry.
Strong expression of PINK1 in the mitochondria and endoplasmImmunocytochemistry reticulim of HeLa cellsFlow Cytometry: 10ug/ml using MCF7 cellsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human PINK1
Isotype：IgG
Calc Applications Abbrev：E FC IF
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-QGKAHLESRSYQEAQ, from the internal region of human PINK1. Species Sequence Homology: rat
