Transcriptional coactivator for steroid receptors and nuclear receptors.
Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter.
Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:64,000Western Blot: 1-3ug/ml, observed in rat stomach lysates on ~100kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes rat PPARGC1A. Species sequence homology: Canine, human and mouse.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-DGLFDDSEDESDK, from rat PPARGC1A, at the internal region of the protein (NP_037393.1).
