Cytoskeletal protein required for organization of normal actin cytoskeleton.
Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types.
May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays.
Binds to proteins that bind to either monomeric or filamentous actin.
Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles.
Different isoforms may have functional differences.
Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.
Involved in targeting ACTN to specific subcellular foci.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000Western Blot: 0.1-0.3ug/ml, observed in human umbillical cord lysates on ~125kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human PALLD. Species sequence homology: Canine, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-RDSGDENEPIQER, from human PALLD, at the internal region of the protein (NP_057165.3).
