Calcium-dependent NADPH oxidase that generates superoxide.
Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa.
May play a role in cell growth and apoptosis.
Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:8000Western Blot: 0.5-2ug/ml, human testis lysates observed on ~90kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human NOX5. Species sequence homology: Bovine and canine.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Ca Hu
Immunogen：Synthetic peptide corresponding to C-EWHPFTISSAPEQKD, from human NOX5, at the internal region of the protein (NP_078781.3, NP_001171708.1, NP_001171709.1).
