Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene.
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions.
ABC proteins transport various molecules across extra- and intracellular membranes.
ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
This gene is a member of the MRP subfamily which is involved in multi-drug resistance.
This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1.
Increased expression of this gene is associated with breast cancer.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes ABCC12. Species sequence homology: Bovine, canine, human, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Bo Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-EFDKPEVLAEKPD, from ABCC12, at the internal region (near C-terminal) of the protein (NP_150229.2).
