84-1226-48 MXD4 (Max Dimerization Protein 4, Max Dimerizer 4, Max-interacting Transcriptional Repressor MAD4, Max-associated Protein 4, Class C Basic Helix-loop-helix Protein 12, bHLHc12, MAD4) 100ug M2450-41D
84-1226-48 MXD4 (Max Dimerization Protein 4, Max Dimerizer 4, Max-interacting Transcriptional Repressor MAD4, Max-associated Protein 4, Class C Basic Helix-loop-helix Protein 12, bHLHc12, MAD4) 100ug M2450-41D
The MAD, basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex.
The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex.
Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Western Blot: 0.5-2ug/ml, observed in human kidney lysates on ~22kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human MXD4.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to GPHCRRLGRPALS, from human MXD4, at C-terminal (NP_006445.1).
