84-1226-42 MARK4 (MAP/Microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/Microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S) 100ug M2408-01B
特徴
- MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain.
- RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
- Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis.
- Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression.
- Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells.
- It has been suggested that MARK4 provides a growth advantage to cells.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:128,000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for at least 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：goat
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
- Specificity：Recognizes human MARK4.
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to IKRKPPPGCSDSPGV, from human MARK4, at C-terminal (NP_113605.2).
- Shelf Life：1year
- Swiss Prot Number：Q96L34
- EU Commodity Code：30021010
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