MAL, a nonglycosylated integral membrane proteolipid, has been identified as a major internal component of glycolipid enriched membrane (GEM) microdomains.
MAL is the first integral membrane proteolipid component to have been shown as a necessary element in the cellular apical sorting apparatus for newly synthesized proteins.
In its steady state this highly hydrophobic proteolipid, resides predominantly in the apical zone of polarized epithelial cells.
It has also been shown in itinerant protein cycling between the plasma membrane and endosomes and in other cells.
This 17kD proteolipid contains four putative transmembrane domains.
These domains along with its protein trafficking properties are defined by the specific signals delegated by its specific aa sequence.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:4000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes MAL. Species sequence homology: Human, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-QDGFTYRHYHEN, from MAL, at the internal region of the protein (NP_002362.1, NP_071884.1).
