May play a role in the phosphorylation of proteins central to Parkinson disease.
Phosphorylates PRDX3.
May also have GTPase activity.
Applications:Suitable for use in Western Blot, ELISA, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:ELISA (Peptide): 1:64,000Western Blot: 0.3-1ug/ml using human brainImmunohistochemistry (Paraffin): 1-2ug/ml using human brain (hippocampus).
Requires HIER using sodium citrate buffer pH 6.0Immunocytochemistry: human neuronsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Specificity:Recognizes human LRRK2.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Bo Hu
Immunogen:Synthetic peptide corresponding to CELAEKMRRTSV, from human LRRK2, at the internal region (near the C-terminal) of the protein. Species Sequence Homology: bovine