Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma).
Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes.
Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa.
Alternatively spliced transcript variants encoding different isoforms have been identified.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes LAMA3. Species sequence homology: Human.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to NNQCHSSHKRRTK, from LAMA3, at the internal region of the protein (NP_937762.1).
