Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis.
A novel KLK gene, KLK12, is expressed in a variety of tissues including salivary gland, stomach, uterus, lung, thymus, prostate, colon, brain, breast, thyroid, and trachea.
It has applications as a novel cancer biomarker.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:4000Western Blot: 0.1-0.3ug/ml, observed in human prostate lysates on ~37kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human KLK5. Species sequence homology: Bovine, canine and rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Ca Hu Rt
Immunogen:Synthetic peptide corresponding to KAGRDSCQGD, from human KLK5, at the internal region of the protein (NP_036559.1).