Associates with IFNAR1 to form the type I interferon receptor.
Receptor for interferons alpha and beta.
Involved in IFN-mediated STAT1, STAT2 and STAT3 activation.
Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1.
Isoform 3 is a potent inhibitor of type I IFN receptor activity.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes IFNAR2. Species sequence homology: Human.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to SYDSPDYTDESCT, from IFNAR2, at the internal region of the protein (NP_000865.2, NP_997467.1, NP_997468.1).