ICAM5 is a member of the intercellular adhesion molecule (ICAM) family.
All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein.
This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes.
It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Immunohistochemistry (Paraffin): 2-4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human ICAM5. Species sequence homology: Bovine, mouse, porcine and rat.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Bo Hu Mo Po Rt
Immunogen：Synthetic peptide corresponding to C-ESPAEGEVFAIQ, from human ICAM5, at C-terminal (NP_003250.3).
