DBNL is an F-actin-binding, cytoskeleton adapter protein, and member of the ABP1 family, implicated in the connection of the actin cytoskeleton to endocytic function, through association with the GTPase dynamin.
DBNL is degraded in a caspase-dependent manner during apoptosis, and may be involved in the reorganization of the actin cytoskeleton.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 1-3ug/ml, observed in Jurkat and 3T3 lysates on ~55kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes DBNL. Species Crossreactivity: Human and mouse. Species sequence homology: Canine and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to AANLSRNGPALQE-C, from DBNL, at N-terminal (NP_054782.2, NP_001014436.1, NP_001116428.1).
