Acts as a repressor of transcriptional activation.
Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription.
Chaperone.
Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:4000Western Blot: 1-3ug/ml, observed in lysates of cell line A431 on ~75kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human HSPA8.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-EKLQGKINDEDKQK, from human HSPA8, at the internal region of the protein (NP_006588.1). Species sequence homology: Canine, mouse and rat.