GPR40 is classified as a Carboxylic Acid GPCR that may be associated with glucose and insulin secretion to regulate pancreatic islet function.
Additional roles in neurological functions have also been speculated.
GPR40 expression has been reported primarily in brain and pancreas.
An EST has been isolated from a pancreatic library.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Western Blot: 0.01-0.03ug/ml, observed in human breast lysates on ~28kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human FFAR1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to CAARTQGGKSQK, from human FFAR1, at C-terminal (NP_005294.1).