This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain.
The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development.
Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.