Inhibits renal tubular phosphate transport by reducing SLC34A1 levels.
Acts directly on the parathyroid to decrease PTH secretion.
Regulator of vitamin-D metabolism.
Negatively regulates osteoblasts differentiation and matrix mineralization.
Upregulates EGR1 expression in the presence of KL.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:16,000Western Blot: 0.5-2ug/ml, observed ~27+38kD bands in mouse brain lysatesOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes mouse Fgf23.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide corresponding to C-ENGYDVYLSQKHH from the internal region of mouse Fgf23 (NP_073148.1). Species sequence homology: rat
