Inhibits renal tubular phosphate transport by reducing SLC34A1 levels.
Upregulates EGR1 expression in the presence of KL.
Acts directly on the parathyroid to decrease PTH secretion.
Regulator of vitamin-D metabolism.
Negatively regulates osteoblast differentiation and matrix mineralization.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:ELISA: 1:32,000Western Blot: 0.5-1.5ug/ml, observed in human brain, hippocampus lysates on ~26-27kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human FGF23.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-RHTRSAEDDSERD, at the internal region of human FGF23.
