Probably involved in connections of major cytoskeletal structures to the plasma membrane.
In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole.
Along with PLEKHG6, required for normal macropinocytosis.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Western Blot: 1-3ug/mlImmunohistochemistry (Paraffin): 3-5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human VIL2. Species sequence homology: Canine.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Ca Hu
Immunogen:Synthetic peptide corresponding to C-QDYEEKTKKAER, from human VIL2, at the internal region of the protein (NP_003370.2).