84-1222-87 E2F8 (Transcription factor E2F8, E2F-8) 100ug E0014-22
特徴
- Along with E2F7, inhibitor of E2F-dependent transcription.
- Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'.
- Directly represses E2F1 transcription.
- Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.
- Applications:Suitable for use in ELISA.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:32,000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for at least 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ug
- Host：goat
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
- Specificity：Recognizes E2F8. Species sequence homology: Human and mouse.
- Isotype：IgG
- Calc Applications Abbrev：E
- Calc Crossreactivity：Hu Mo
- Immunogen：Synthetic peptide corresponding to C-KSIESDRRKINSAPS , from E2F8, at the internal region of the protein (NP_078956.2).
- Shelf Life：1year
- EU Commodity Code：30021010
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