The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family.
The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells.
This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2.
This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:32,000Immunohistochemistry (Paraffin): 4-6ug/ml Requires HIER using Tris/EDTA buffer pH 9Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human DUOX1.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to EKFQRSCLHQTVQ, from human DUOX1, at the internal region of the protein.
