アズワンのAXELショップ
試薬
特定メーカー試薬
US Biological(antibodypab)
84-1222-30 CYP3A4 (Albendazole Monooxygenase, Albendazole Sulfoxidase, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Nifedipine Oxidase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6-alpha-hydroxylase, CYP3A3) 100ug C9095-17A3
84-1222-30 CYP3A4 (Albendazole Monooxygenase, Albendazole Sulfoxidase, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450-PCN1, Nifedipine Oxidase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6-alpha-hydroxylase, CYP3A3) 100ug C9095-17A3
特徴
Cytochromes P450 are a group of heme-thiolate monooxygenases.
In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.
It performs a variety of oxidation reactions (e.g.
caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
The enzyme also hydroxylates etoposide.
Applications:Suitable for use in Peptide ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Peptide ELISA: 1:8000Western Blot: 0.3ug/ml.
A band at 26-27kD was detected in human liver lysateOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human CYP3A4. It is not expected to crossreact with 3A5, 3A7 or 3A43.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to C-KESRLEDTQKHR at the internal region of human CYP3A4 (NP_059488.2).
Shelf Life:1year
EU Commodity Code:30021010
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