Cadherin E (uvomorulin, cell-CAM120/80) is a calcium dependent cell adhesion molecule expressed predominately in epithelial tissues.
It plays an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity.
Numerous studies have demonstrated that reduction and/or loss of Cadherin E expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Western Blot: 0.3-1ug/ml, human kidney lysates observed on ~97kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human CDH1. Species sequence homology: Rat, canine and porcine.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Po Rt
Immunogen：Synthetic peptide corresponding to C-DYKINLKLMDNQNK, from CDHE, at the internal region of the protein (NP_004351.1).
