This gene belongs to the DAZ gene family required for germ cell development.
It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like).
Loss of this gene function results in the absence of sperm in semen (azoospermia).
Histological studies demonstrated that the primary defect is at the meiotic G2/M transition.
Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes BOLL. Species sequence homology: Bovine, canine and human.
Isotype:IgG
Calc Applications Abbrev:E
Calc Crossreactivity:Bo Ca Hu
Immunogen:Synthetic peptide corresponding to C-QPEPIKTVWSIHY, from BOLL, at C-terminal (NP_932074.1, NP_149019.1).