Probable C to U editing enzyme whose physiological substrate is not yet known.
Does not display detectable apoB mRNA editing.
Has a low intrinsic cytidine deaminase activity.
May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Western Blot: 1-3ug/ml, observed in human skeletal muscle lysates on ~26kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human APOBEC2. Species sequence homology: Bovine, mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Hu Mo Rt
Immunogen:Synthetic peptide corresponding to C-KPQDFEYVWQN, from human APOBEC2, at the internal region of the protein (NP_006780.1).