Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor.
AIbZIP is a 395aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor.
It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain.
Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells; full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear.
AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.5-2ug/ml, observed in human placenta lysate on ~50kD bandsImmunohistochemistry (Paraffin): 2-4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human AIBZIP.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-PSGRIRSVLHADEM, from human AIBZIP, at C-terminal (NP_570968.1).
Shelf Life：1year
EU Commodity Code：30021010
商品名：AIBZIP (CREB3L4, Cyclic AMP-responsive Element-binding Protein 3-like Protein 4, cAMP-responsive Element-binding Protein 3-like Protein 4, Androgen-induced Basic Leucine Zipper Protein, AIbZIP, Attaching to CRE-like 1, ATCE1, Cyclic AMP-responsive Element-binding Protein 4, CREB-4, cAMP-responsive Element-binding Protein 4, Transcript Induced in Spermiogenesis Protein 40, Tisp40, hJAL, CREB4, JAL) 100ug
