TNFR2 is a 75kD transmembrane glycoprotein that also exists as a secreted protein.
TNF receptors self assemble through a distinct functional extracellular domain termed PLAD in the absence of ligand.
Efficient TNFA binding depends on receptor self assembly.
TNFR2 has been shown to be responsible for stimulation of activated T lymphocytes by TNFalpha.
Applications:Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 1:50Western Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：250ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4.
Specificity：Recognizes mouse TNF-R2. Species sequence homology: human and rat.
Isotype：IgG
Calc Applications Abbrev：IHC IP WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide corresponding to the C-terminal of mouse TNF-R2.
