TRPC4 (or short transient receptor potential channel, TRP) contains 6 transmembrane domains, a pore region, a caveolin-binding domain and a PDZ binding domain at the C-terminus.
It is a non-selective calcium permeant cation channel probably regulated by phosphatidylinositol second messengers via GPCRs or tyrosine kinases or depletion of internal calcium stores.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.3-1ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 4.75ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human TRPC4. Species sequence homology: bovine, canine, mouse, porcine and rat.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide C-KHAKEEDSSIDYD from an internal region (near C-terminus) of human TRPC4.
