Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters.
Slc1a5 has a preference for transporting zwitter ions.
Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses.
In addition, it has been associated with increased metabolism in malignant tumors.
In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 15-20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human SLC1A5.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 17aa from internal domain of human SLC1A5.