84-1218-32　［取扱停止］RBBP8, ID (DNA Endonuclease RBBP8, CtBP-interacting Protein, CtIP, Retinoblastoma-binding Protein 8, RBBP-8, Retinoblastoma-interacting Protein and Myosin-like, RIM, Sporulation in the Absence of SPO11 Protein 2 Homolog, SAE2, CTIP) 50ug　R1665-38A

特徴

• Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by ensuring both resection and intrachromosomal association of the broken ends.
• Promotes ATR and RPA recruitment to DSBs in S/G2 phase and facilitates the generation of ssDNA.
• May modulate the functions ascribed to BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.