Catalyzes the release of fatty acids from phospholipids.
It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production.
May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells.
Has a role in cardiolipin (CL) deacylation.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 1:200-1:400Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:1Ea
Host:rabbit
Source Antibody:hamster
Grade:Serum
Purity:Serum
Form:Supplied as a liquid.
Specificity:Recognizes hamster iPLA2. Species sequence homology: bovine, human, mouse, rat, sheep.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hm
Immunogen:Synthetic peptide corresponding to aa557-576 from hamster PLA2G6.