84-1217-96　［取扱停止］NALP8, NT (NACHT, LRR and PYD Domains-containing Protein 8, Nucleotide-binding Oligomerization Domain Protein 16, PYRIN and NACHT-containing Protein 4, NLRP8, NOD16, PAN4) 50ug　N0018-69B

特徴

• NALP8, like other NALP proteins, is a cytoplasmic protein that forms a subfamily within the larger CATERPILLER protein family.
• NALP8 is a short NALP, with an N-terminal pyrin (MEFV) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region.
• Though the exact function of NALP8 is yet unknown reports suggest that it may be involved in the activation of proinflammatory caspases (e.g., CASP1) via their involvement in multiprotein complexes called inflammasomes.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.