MMP-12 degrads extracellular matrix components such as elastin and is involved in tissue remodeling processes.
MMP12 is a proteolytic enzyme responsible for cleavage of plasminogen to angiotensin.
Studies using animal models of acute and chronic pulmonary inflammatory diseases, have given evidences that MMP-12 is an important mediator of the pathogenesis of these diseases.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% thimerosal, 30% glycerol.
Specificity：Recognizes human MMP12.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 460aa from human MMP-12. Species sequence homology: mouse.
