Human fibroblast stromelysin/MMP3 is a proteoglycanase with a wide range of substrate specificities.
It is a secreted metalloprotease produced predominantly by connective tissue cells.
MMP3 is capable of degrading proteoglycan, fibronectin, laminin, and type IV collagen.
Expression has been documented in breast carcinoma, wound healing and chronic inflammatory diseases.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-4ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:rat
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
Specificity:Recognizes rat MMP-3.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Rt
Immunogen:Synthetic peptide corresponding to 465aa from rat MMP-3. Species sequence homology: human, mouse, equine and rabbit.