DPP10 shares structural similarity with the dipeptidyl peptidase family, however it lacks the active site serine, which is substituted with a glycine residue.
DPP10 has been shown to facilitate Kv4.2 protein trafficking to the cell membrane, increase A-type current magnitude and modify the voltage dependence and kinetic properties of the Kv4.2 channel.
DPP10 is prominently expressed in all brain regions examined except cerebellum.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.1-0.3ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human DPP10. Species sequence homology: bovine and canine.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide C-DEGHNVSEKSKYHL from an internal region of human DPP10.