RDC1 was originally considered to be an Adrenomedullin receptor that binds calcitonin gene-related peptide (CGRP) and adrenomedullin.
RDC1 and GPRN1 represent two tissue-specific subtypes of the same 60kD receptor.
RDC1 has the structural characteristics of a chemokine receptor.
Recently it has been shown that RDC1 binds to the chemokine CXCL12 and should be considered to be a chemokine receptor.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Western Blot: 1:500-1:1000Immunofluorescence: 1:100-1:500Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CXCR7. Species sequence homology: mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CXCR7.
