84-1216-29　PNP (Purine Nucleoside Phosphorylase, Inosine Phosphorylase, NP) 100ug　P4350-11

特徴

• Purine Nucleoside Phosphorylase (PNP) catalyzes the phophorolysis of N-ribosidic bonds of purine nucleosides and deoxynucleosides.
• Physiological substrates of PNP include inosine, guanosine, and 2'-deoxyguanosine, but not adenosine.
• PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues.
• Genetic deficiencies of PNP result in severely compromised T-lymphocyte function and neurologic dysfunction.
• PNP is used in assays for the measurement of inorganic phosphate.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.