84-1216-26　PGPEP1 (Pyroglutamyl-peptidase 1, 5-oxoprolyl-peptidase, Pyroglutamyl Aminopeptidase I, PAP-I, Pyroglutamyl-peptidase I, PGP-I, Pyrrolidone-carboxylate Peptidase, PGPI) 100ug　P3365-15

特徴

• Pyroglutamyl peptidase-1 is an omega peptidase which removes pyroglutamyl residues from the amino termini of peptides and proteins.
• It is a cytosolic cysteine peptidase that is expressed in most cell types.
• The enzyme requires a thiol-reducing agent for activity.
• PGPEP-1 is potentially involved in the inactivation of biologically active peptides that possess an a terminal pyroglutamyl group.
• Examples of such peptides include neurotensin, luteinizing hormone releasing hormone, and thyrotropin-releasing hormone.
• Human and mouse PGPEP-1 share 95%aa sequence identity.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.