LRRN1 is a 95kD member of the neuronal LRR family of proteins.
It is a cell-surface glycoprotein that is expressed on embryonic motor neurons and somatic myoblasts.
Human LRRN1 is 716aa in length.
It is a type I transmembrane protein that contains a 606aa extracellular region aa26-631 and a short 64aa cytoplasmic tail.
The extracellular region shows eleven LRRs aa94-384 that mediate protein-protein interactions, one C2-type Ig-like domain and one fibronectin type III domain.
There is one potential alternate start site at Met286.
Over aa26-631, human LRRN1 shares 96% aa sequence identity with mouse LRRN1.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1ug/mlImmunohistochemistry: 5-15ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：sheep
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.2mg/ml.
Specificity：Recognizes human LRRN1. Species sequence homology: Recombinant human NLRR-3 (5%).
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant corresponding to aa26-631 from human LRRN1 expressed in NSO cell line.
