Thought to form a receptor-activated non-selective calcium permeant cation channel.
Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.
Seems to be also activated by intracellular calcium store depletion.
Applications:Suitable for use in Immunohistochemistry, ELISA and Immunofluorescence.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry (FFPE): 3.75ug/ml Requires HIER citrate buffer, pH 6.0ELISA (Peptide): 1:32,000Immunofluorescence: 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human TRPC1. Species Crossreactivity: monkey, mouse, rat, canine, bovine, equine, rabbit, porcine and chicken
Isotype:IgG
Calc Applications Abbrev:E IF IHC
Calc Crossreactivity:Bo Ca Ch Eq Hu Mk Mo Po Rb Rt
Immunogen:Synthetic peptide corresponding to aa722-733, C-NLKQKRDENYQK, in the internal region of human TRPC1.