84-1210-71　GPER (G-protein Coupled Estrogen Receptor 1, Chemoattractant Receptor-like 2, Flow-induced Endothelial G-protein Coupled Receptor 1, FEG-1, G-protein Coupled Receptor 30, GPCR-BR, IL8-related Receptor DRY12, Lymphocyte-derived G-protein Coupled Receptor, LYGPR, Membrane Estrogen Receptor, mER, CEPR, CMKRL2, DRY12, GPR30) 50ug　G8600-34L

特徴

• GPR30 (G Protein-coupled Receptor 30), also known as G Protein-coupled estrogen Receptor 1 (GPER), is a member of G protein-coupled receptor family.
• It contains seven hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops.
• GPR30 transduces a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins.
• GPR30 is an orphan receptor and localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives.
• Activating GPR30 via estrogen results in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 3.75-7.5ug/ml Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.