CD178 cell surface antigen is a 40kD glycoprotein also known as Fas ligand (CD95L).
CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells.
The protein may exist as either a membrane bound or a cleaved soluble form.
CD178 plays an important role in T cell development and cytotoxicity.
Binding of CD178 to Fas (CD95) results in the induction of apoptosis.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:3000Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in 0.1M Tris-glycine, pH 7.0, 0.01% thimerosal, 10% glycerol.
Specificity:Recognizes human FASLG.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to human FASLG conjugated to KLH.