Calretinin (CAB29, calbindin 2) is a calcium binding protein that belongs to calbindin family.
It is mainly found in neuronal tissue, high expressed in auditory neurons.
It has been implicated in as a calcium buffer, calcium sensor, and as a regulator of apoptosis.
Calretinin is considered as a specific marker of mesothelllal cells; it is the only marker that has the utility in distinguishing between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas.
It is widely used in the panel of makers for distinguishing mesothlioma from adenocarcinoma.
Along with calretinin, the panel includes E-cadherin and cytokeratin 5/6.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:100-1:200Western Blot: 1:500-1:3000Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-glycine, pH 7.0, 0.01% thimerosal, 10% glycerol.
Specificity：Recognizes human Calretinin. Species sequence homology: Mouse (98%), rat (98%), bovine (97%).
Isotype：IgG
Calc Applications Abbrev：IC IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant corresponding to human Calretinin.
