TYK2, a TYK2/JAK type protein kinase, is associated with signal transduction via cytokine receptors and mediating the activation of STAT (signal transducers and activators of transcription) proteins.
TYK2 has been shown to phosphorylate the interferon-alpha/beta receptor alpha chain and to be a physiological substrate of protein tyrosine phosphatase PTP1B.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human TYK2. Species sequence homology: Mouse and rat.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic non-phosphopeptide corresponding to aa surrounding Tyr1054 of human TYK2 (KLH).
