The protein encoded by this gene belongs to the TRIM protein family.
It has multiple zinc finger motifs and a leucine zipper motif.
It has been proposed to form homo- or heterodimers, which are involved in nucleic acid binding.
Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation.
It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (Formalin-fixed, paraffin-embedded): 10ug/ml Immunocytochemistry: 20ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human TRIM25. Species sequence homology: mouse
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 19aa from near the C-terminal of human TRIM25 (KLH).